2xng

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xng.jpg|left|200px]]
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The entry 2xng is ON HOLD until Paper Publication
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{{STRUCTURE_2xng| PDB=2xng | SCENE= }}
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Authors: Kosmopoulou, M., Bayliss, R.
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===STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR===
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Description: Structure of Aurora-A bound to a selective imidazopyrazine inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:16:58 2010''
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{{ABSTRACT_PUBMED_20833547}}
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==About this Structure==
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2XNG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNG OCA].
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==Reference==
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<ref group="xtra">PMID:20833547</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Bayliss, R.]]
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[[Category: Kosmopoulou, M.]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Cytoskeleton]]
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[[Category: Kinase]]
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[[Category: Microtubule]]
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[[Category: Mitosis]]
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[[Category: Proto-oncogene]]
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[[Category: Ser-thr protein kinase complex]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:43:30 2010''

Revision as of 11:34, 22 September 2010

Image:2xng.jpg

Template:STRUCTURE 2xng

STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR

Template:ABSTRACT PUBMED 20833547

About this Structure

2XNG is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bouloc N, Large JM, Kosmopoulou M, Sun C, Faisal A, Matteucci M, Reynisson J, Brown N, Atrash B, Blagg J, McDonald E, Linardopoulos S, Bayliss R, Bavetsias V. Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg Med Chem Lett. 2010 Oct 15;20(20):5988-93. Epub 2010 Aug 21. PMID:20833547 doi:10.1016/j.bmcl.2010.08.091

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