3nsh

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3nsh.jpg|left|200px]]
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The entry 3nsh is ON HOLD until Paper Publication
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{{STRUCTURE_3nsh| PDB=3nsh | SCENE= }}
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Authors: Probst, G.D., Bowers, S., Sealy, J.M., Brecht, E., Yao, N.
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===BACE-1 in complex with ELN475957===
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Description: BACE-1 in complex with ELN475957
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:25:54 2010''
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The line below this paragraph, {{ABSTRACT_PUBMED_20822903}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_20822903}}
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==About this Structure==
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3NSH is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSH OCA].
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==Reference==
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<ref group="xtra">PMID:20822903</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Bowers, S.]]
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[[Category: Brecht, E.]]
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[[Category: Probst, G D.]]
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[[Category: Sealy, J M.]]
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[[Category: Yao, N.]]
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[[Category: Asp 2]]
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[[Category: Asp2]]
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[[Category: Aspartyl protease 2]]
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[[Category: Beta-site amyloid precursor protein cleaving enzyme 1]]
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[[Category: Beta-site app cleaving enzyme 1]]
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[[Category: Hydrolase]]
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[[Category: Memapsin-2]]
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[[Category: Membrane-associated aspartic protease 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:47:45 2010''

Revision as of 11:38, 22 September 2010

Image:3nsh.jpg

Template:STRUCTURE 3nsh

BACE-1 in complex with ELN475957

Template:ABSTRACT PUBMED 20822903

About this Structure

3NSH is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Probst GD, Bowers S, Sealy JM, Stupi B, Dressen D, Jagodzinska BM, Aquino J, Gailunas A, Truong AP, Tso L, Xu YZ, Hom RK, John V, Tung JS, Pleiss MA, Tucker JA, Konradi AW, Sham HL, Jagodzinski J, Toth G, Brecht E, Yao N, Pan H, Lin M, Artis DR, Ruslim L, Bova MP, Sinha S, Yednock TA, Gauby S, Zmolek W, Quinn KP, Sauer JM. Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Structure-activity relationship of the aryl region. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6034-9. Epub 2010 Aug 19. PMID:20822903 doi:10.1016/j.bmcl.2010.08.070

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