1psr
From Proteopedia
(New page: 200px<br /> <applet load="1psr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1psr, resolution 1.05Å" /> '''HUMAN PSORIASIN (S1...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1PSR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]] with HO as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1PSR OCA]]. | + | 1PSR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]] with HO as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: HO. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1PSR OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: s100 protein family]] | [[Category: s100 protein family]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:01:13 2007'' |
Revision as of 08:56, 30 October 2007
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HUMAN PSORIASIN (S100A7)
Overview
BACKGROUND: The S100 family consists of small acidic proteins, belonging, to the EF-hand class of calcium-binding proteins. They are primarily, regulatory proteins, involved in cell growth, cell structure regulation, and signal transduction. Psoriasin (S100A7) is an 11.7 kDa protein that is, highly upregulated in the epidermis of patients suffering from the chronic, skin disease psoriasis. Although its exact function is not known, psoriasin is believed to participate in the biochemical response which, follows transient changes in the cellular Ca2+ concentration. RESULTS: The, three-dimensional structure of holmium-substituted psoriasin has been, determined by multiple anomalous wavelength dispersion (MAD) phasing and, refined to atomic resolution (1.05 A). The structure represents the ... [(full description)]
About this Structure
1PSR is a [Single protein] structure of sequence from [Homo sapiens] with HO as [ligand]. Structure known Active Site: HO. Full crystallographic information is available from [OCA].
Reference
EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing., Brodersen DE, Etzerodt M, Madsen P, Celis JE, Thogersen HC, Nyborg J, Kjeldgaard M, Structure. 1998 Apr 15;6(4):477-89. PMID:9562557
Page seeded by OCA on Tue Oct 30 11:01:13 2007
