2f3g

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(New page: 200px<br /> <applet load="2f3g" size="450" color="white" frame="true" align="right" spinBox="true" caption="2f3g, resolution 2.13&Aring;" /> '''IIAGLC CRYSTAL FORM...)
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==About this Structure==
==About this Structure==
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2F3G is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.69 2.7.1.69]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F3G OCA]].
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2F3G is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Active as [[http://en.wikipedia.org/wiki/Protein-N(pi)-phosphohistidine--sugar_phosphotransferase Protein-N(pi)-phosphohistidine--sugar phosphotransferase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.69 2.7.1.69]]. Structure known Active Site: AVE. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2F3G OCA]].
==Reference==
==Reference==
Structural studies of the Escherichia coli signal transducing protein IIAGlc: implications for target recognition., Feese MD, Comolli L, Meadow ND, Roseman S, Remington SJ, Biochemistry. 1997 Dec 23;36(51):16087-96. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9405042 9405042]
Structural studies of the Escherichia coli signal transducing protein IIAGlc: implications for target recognition., Feese MD, Comolli L, Meadow ND, Roseman S, Remington SJ, Biochemistry. 1997 Dec 23;36(51):16087-96. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9405042 9405042]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Protein-N(pi)-phosphohistidine--sugar phosphotransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Comolli, L.]]
[[Category: Comolli, L.]]
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[[Category: signal transduction]]
[[Category: signal transduction]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:13:14 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:02:17 2007''

Revision as of 08:57, 30 October 2007


2f3g, resolution 2.13Å

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IIAGLC CRYSTAL FORM III

Overview

In Escherichia coli, the glucose-specific phosphocarrier protein of the, phosphotransferase system (PTS), IIAGlc (IIIGlc in older literature), is, also the central regulatory protein of the PTS. Depending upon its state, of phosphorylation, IIAGlc binds to a number of different proteins that, display no apparent sequence homology. Previous structural studies, suggested that nonspecific hydrophobic interactions, specific salt, bridges, and an intermolecular Zn(II) binding site contribute to the wide, latitude in IIAGlc binding sites. Two new crystal forms of IIAGlc have, been solved at high resolution, and the models were compared to those, previously studied. The major intermolecular contacts in the crystals, differ in detail, but all involve the hydrophobic active site of IIAGlc, ... [(full description)]

About this Structure

2F3G is a [Single protein] structure of sequence from [Escherichia coli]. Active as [Protein-N(pi)-phosphohistidine--sugar phosphotransferase], with EC number [2.7.1.69]. Structure known Active Site: AVE. Full crystallographic information is available from [OCA].

Reference

Structural studies of the Escherichia coli signal transducing protein IIAGlc: implications for target recognition., Feese MD, Comolli L, Meadow ND, Roseman S, Remington SJ, Biochemistry. 1997 Dec 23;36(51):16087-96. PMID:9405042

Page seeded by OCA on Tue Oct 30 11:02:17 2007

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