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Sandbox 32

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{{STRUCTURE_1a4v | PDB=1a4v | SCENE= }}
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{{Template:Oberholser_Sandbox_Reservation}}
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=Alpha Lactalbumin=
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Alpha Lactalbumin is an important whey protein that can be found in the milk of many mammalian species. In primates (and humans), lactalbumin increases the production of lactose, a milk sugar, and its regulation is controlled by the hormone prolactin. An interesting characteristic of lactalbumin is that it can strongly bind calcium and zinc ions and it is possible that it possesses antitumor and bactericidal properties.
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=Secondary Structure=
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<scene name='Sandbox_32/1a4v_secondary_structure/1'>Lactalbumin secondary structure</scene> This model shows the secondary structure of 1a4v. Alpha helices are shown as magenta rockets and beta sheets are shown as yellow arrows. Notice the beta sheets are running in opposite directions. (anti-parallel).
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=Polar and Non Polar Groups=
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<scene name='Sandbox_32/1a4v_polar_and_nonpolar_groups/1'>Lactalbumin Polar and Non polar groups</scene> This model shows the polar regions (charged or uncharged) in pink and the nonpolar regions in gray. Notice the polar groups are mostly on the outside while the non polar groups are clumped together and are mostly internal. Having the non polar groups together on the interior is more energetically efficient.
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=Ligands on Lactalbumin=
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<scene name='Sandbox_38/Ligands_with_contacts/3'>Lactalbumin ligands with their contacting molecules</scene> This model shows the two ligands on 1a4v and their surrounding molecules. The two ligands are composed of Calcium.
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=Charged residues on Lactalbumin=
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<scene name='Sandbox_38/Charged/1'>Lactalbumin charged residues</scene> This model shows the charged residues of 1a4v. Cations are blue, anions are red, and polar but uncharged side chains are light purple.
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=Amino to Carboxy Direction=
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<scene name='Sandbox_31/Terminus/1'>Lactalbumin amino and carboxy terminals</scene> The blue end of this model signifies the amino terminus of the protein (5' ends of the nucleic acid) and the red end signifies the carboxy terminus of the protein (3' end of the nucleic acid).
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This page was made by Louis Wenger on September 20, 2009.
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Revision as of 15:45, 8 October 2010

Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.
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