Talk:Phosphofructokinase (PFK)

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m (New page: I don't understand this statement: "The PFK reaction is strongly exergonic (irreversible) under physiological conditions and hence is one of the glycolytic pathway's rate-determining step...)
Current revision (00:56, 13 October 2010) (edit) (undo)
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"The PFK reaction is strongly exergonic (irreversible) under physiological conditions and hence is one of the glycolytic pathway's rate-determining steps."
"The PFK reaction is strongly exergonic (irreversible) under physiological conditions and hence is one of the glycolytic pathway's rate-determining steps."
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The fact that the reaction is strongly exergonic suggests that it should be extremely rapid, assuming the Hammond postulate. In the absence of the Hammond postulate, the speed of a reaction and its exergonicity are not causally related. Cheers, [[User:Michael Evans|mevans]] 02:55, 13 October 2010 (IST)
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The fact that the reaction is strongly exergonic suggests that it should be extremely rapid, assuming the Hammond postulate. In the absence of the Hammond postulate, the speed of a reaction and its exergonicity are not causally related. Should that say "endergonic"? Cheers, [[User:Michael Evans|mevans]] 02:55, 13 October 2010 (IST)

Current revision

I don't understand this statement:

"The PFK reaction is strongly exergonic (irreversible) under physiological conditions and hence is one of the glycolytic pathway's rate-determining steps."

The fact that the reaction is strongly exergonic suggests that it should be extremely rapid, assuming the Hammond postulate. In the absence of the Hammond postulate, the speed of a reaction and its exergonicity are not causally related. Should that say "endergonic"? Cheers, mevans 02:55, 13 October 2010 (IST)

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