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Cathepsin

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(New page: Crystal structure wild-type human procathepsin B, 1pbh {{STRUCTURE_1pbh| PDB=1pbh | SIZE=300| SCENE= |right|CAPTION=human procathepsin B, 1pbh...)
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Revision as of 06:46, 13 October 2010

Image:1pbh.png
Crystal structure wild-type human procathepsin B, 1pbh

Template:STRUCTURE 1pbh

Cathepsin (CTS) is a protease which becomes activated at low pH. It is found in lysosomes. Members of the CTS group are denoted as CTSA, CTSB etc and cleave proteins at different peptide bonds. The CTSs are expressed as an inactive precursor pro-CTS (PCTS) which become active when a long residue prosegment is cleaved off producing the mature CTS (MCTS).

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