2xem

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xem.jpg|left|200px]]
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The entry 2xem is ON HOLD until Paper Publication
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{{STRUCTURE_2xem| PDB=2xem | SCENE= }}
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Authors: Liew, C.W., Sharff, A., Kotaka, M., Kong, R., Bricogne, G., Liang, Z.X., Lescar, J.
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===INDUCED-FIT AND ALLOSTERIC EFFECTS UPON POLYENE BINDING REVEALED BY CRYSTAL STRUCTURES OF THE DYNEMICIN THIOESTERASE===
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Description: Induced-fit and allosteric effects upon polyene binding revealed by crystal structures of the Dynemicin thioesterase
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:25:49 2010''
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{{ABSTRACT_PUBMED_20888341}}
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==About this Structure==
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2XEM is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Micromonospora_chersina Micromonospora chersina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEM OCA].
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==Reference==
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<ref group="xtra">PMID:20888341</ref><ref group="xtra">PMID:19357082</ref><references group="xtra"/>
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[[Category: Micromonospora chersina]]
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[[Category: Bricogne, G.]]
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[[Category: Kong, R.]]
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[[Category: Kotaka, M.]]
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[[Category: Lescar, J.]]
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[[Category: Liang, Z X.]]
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[[Category: Liew, C W.]]
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[[Category: Sharff, A.]]
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[[Category: Biosynthetic protein]]
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[[Category: Enediyne antitumor agent]]
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[[Category: Polyketide biosynthesis]]
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[[Category: Thioesterase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:45:26 2010''

Revision as of 07:35, 13 October 2010

Image:2xem.jpg

Template:STRUCTURE 2xem

INDUCED-FIT AND ALLOSTERIC EFFECTS UPON POLYENE BINDING REVEALED BY CRYSTAL STRUCTURES OF THE DYNEMICIN THIOESTERASE

Template:ABSTRACT PUBMED 20888341

About this Structure

2XEM is a 4 chains structure with sequences from Micromonospora chersina. Full crystallographic information is available from OCA.

Reference

  • Liew CW, Sharff A, Kotaka M, Kong R, Sun H, Qureshi I, Bricogne G, Liang ZX, Lescar J. Induced-fit upon Ligand Binding Revealed by Crystal Structures of the Hot-dog Fold Thioesterase in Dynemicin Biosynthesis. J Mol Biol. 2010 Oct 1. PMID:20888341 doi:10.1016/j.jmb.2010.09.041
  • Kotaka M, Kong R, Qureshi I, Ho QS, Sun H, Liew CW, Goh LP, Cheung P, Mu Y, Lescar J, Liang ZX. Structure and catalytic mechanism of the thioesterase CalE7 in enediyne biosynthesis. J Biol Chem. 2009 Jun 5;284(23):15739-49. Epub 2009 Apr 8. PMID:19357082 doi:10.1074/jbc.M809669200

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