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3mvm

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3mvm.jpg|left|200px]]
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The entry 3mvm is ON HOLD until Paper Publication
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{{STRUCTURE_3mvm| PDB=3mvm | SCENE= }}
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Authors: Sack, J.S.
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===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V===
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Description: P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:42:01 2010''
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{{ABSTRACT_PUBMED_20804198}}
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==About this Structure==
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3MVM is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVM OCA].
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==Reference==
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<ref group="xtra">PMID:20804198</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Mitogen-activated protein kinase]]
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[[Category: Sack, J S.]]
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[[Category: Kinase]]
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[[Category: P38 map kinase]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:47:55 2010''

Revision as of 07:38, 13 October 2010

Template:STRUCTURE 3mvm

P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V

Template:ABSTRACT PUBMED 20804198

About this Structure

3MVM is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liu C, Lin J, Wrobleski ST, Lin S, Hynes J, Wu H, Dyckman AJ, Li T, Wityak J, Gillooly KM, Pitt S, Shen DR, Zhang RF, McIntyre KW, Salter-Cid L, Shuster DJ, Zhang H, Marathe PH, Doweyko AM, Sack JS, Kiefer SE, Kish KF, Newitt JA, McKinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[ 1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39. PMID:20804198 doi:10.1021/jm100540x

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