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2wxu

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===CLOSTRIDIUM PERFRINGENS ALPHA-TOXIN STRAIN NCTC8237 MUTANT T74I===
===CLOSTRIDIUM PERFRINGENS ALPHA-TOXIN STRAIN NCTC8237 MUTANT T74I===
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{{ABSTRACT_PUBMED_20944240}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:9699639</ref><ref group="xtra">PMID:8934672</ref><references group="xtra"/>
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<ref group="xtra">PMID:20944240</ref><ref group="xtra">PMID:9699639</ref><ref group="xtra">PMID:8934672</ref><references group="xtra"/>
[[Category: Clostridium perfringens]]
[[Category: Clostridium perfringens]]
[[Category: Phospholipase C]]
[[Category: Phospholipase C]]
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[[Category: Virulence]]
[[Category: Virulence]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:40:19 2010''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:24:21 2010''

Revision as of 08:13, 27 October 2010

Image:2wxu.png

Template:STRUCTURE 2wxu

CLOSTRIDIUM PERFRINGENS ALPHA-TOXIN STRAIN NCTC8237 MUTANT T74I

Template:ABSTRACT PUBMED 20944240

About this Structure

2WXU is a 1 chain structure with sequence from Clostridium perfringens. Full crystallographic information is available from OCA.

Reference

  • Vachieri SG, Clark GC, Alape-Giron A, Flores-Diaz M, Justin N, Naylor CE, Titball RW, Basak AK. Comparison of a nontoxic variant of Clostridium perfringens alpha-toxin with the toxic wild-type strain. Acta Crystallogr D Biol Crystallogr. 2010 Oct;66(Pt 10):1067-74. Epub 2010, Sep 18. PMID:20944240 doi:10.1107/S090744491003369X
  • Naylor CE, Eaton JT, Howells A, Justin N, Moss DS, Titball RW, Basak AK. Structure of the key toxin in gas gangrene. Nat Struct Biol. 1998 Aug;5(8):738-46. PMID:9699639 doi:10.1038/1447
  • Nagahama M, Sakurai J. Threonine-74 is a key site for the activity of Clostridium perfringens alpha-toxin. Microbiol Immunol. 1996;40(3):189-93. PMID:8934672

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