2r82

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==About this Structure==
==About this Structure==
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2R82 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_symbiosum Clostridium symbiosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R82 OCA].
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2R82 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_symbiosum Clostridium symbiosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R82 OCA].
==Reference==
==Reference==
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[[Category: Remote active site]]
[[Category: Remote active site]]
[[Category: Swiveling domain]]
[[Category: Swiveling domain]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:14:52 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:32:11 2010''

Revision as of 08:21, 27 October 2010

Image:2r82.png

Template:STRUCTURE 2r82

Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state

Template:ABSTRACT PUBMED 18052212

About this Structure

2R82 is a 1 chain structure with sequence from Clostridium symbiosum. Full crystallographic information is available from OCA.

Reference

  • Lim K, Read RJ, Chen CC, Tempczyk A, Wei M, Ye D, Wu C, Dunaway-Mariano D, Herzberg O. Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry. 2007 Dec 25;46(51):14845-53. Epub 2007 Dec 4. PMID:18052212 doi:http://dx.doi.org/10.1021/bi701848w
  • Herzberg O, Chen CC, Liu S, Tempczyk A, Howard A, Wei M, Ye D, Dunaway-Mariano D. Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis. Biochemistry. 2002 Jan 22;41(3):780-7. PMID:11790099
  • Herzberg O, Chen CC, Kapadia G, McGuire M, Carroll LJ, Noh SJ, Dunaway-Mariano D. Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2652-7. PMID:8610096
  • McGuire M, Huang K, Kapadia G, Herzberg O, Dunaway-Mariano D. Location of the phosphate binding site within Clostridium symbiosum pyruvate phosphate dikinase. Biochemistry. 1998 Sep 29;37(39):13463-74. PMID:9753432 doi:http://dx.doi.org/10.1021/bi980920i
  • Wei M, Li Z, Ye D, Herzberg O, Dunaway-Mariano D. Identification of domain-domain docking sites within Clostridium symbiosum pyruvate phosphate dikinase by amino acid replacement. J Biol Chem. 2000 Dec 29;275(52):41156-65. PMID:10995759 doi:http://dx.doi.org/10.1074/jbc.M006149200

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