3knx

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3knx.jpg|left|200px]]
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The entry 3knx is ON HOLD until Paper Publication
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{{STRUCTURE_3knx| PDB=3knx | SCENE= }}
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Authors: Venkatraman, S., Velazquez, F., Wu, W., Blackman, M., Chen, K.X., Bogen, S., Nair, L., Tong, X., Chase, R., Hart, A., Agrawal, S., Pichardo, J., Prongay, A., Cheng, K.-C., Girijavallabhan, V., Piwinski, J., Shih, N.-Y., Njoroge, F.G.
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===HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor===
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Description: HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:43:19 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 19102654 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19102654}}
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==About this Structure==
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3KNX is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNX OCA].
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==Reference==
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<ref group="xtra">PMID:19102654</ref><references group="xtra"/>
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[[Category: Hepatitis c virus subtype 1a]]
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[[Category: Agrawal, S.]]
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[[Category: Blackman, M.]]
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[[Category: Bogen, S.]]
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[[Category: Chase, R.]]
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[[Category: Chen, K X.]]
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[[Category: Cheng, K C.]]
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[[Category: Girijavallabhan, V.]]
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[[Category: Hart, A.]]
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[[Category: Nair, L.]]
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[[Category: Njoroge, F G.]]
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[[Category: Pichardo, J.]]
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[[Category: Piwinski, J.]]
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[[Category: Prongay, A.]]
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[[Category: Shih, N Y.]]
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[[Category: Tong, X.]]
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[[Category: Velazquez, F.]]
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[[Category: Venkatraman, S.]]
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[[Category: Wu, W.]]
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[[Category: Atp-binding]]
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[[Category: Envelope protein]]
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[[Category: Helicase]]
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[[Category: Hepatitis c virus]]
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[[Category: Hydrolase]]
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[[Category: Macrocyclic ketoamide inhibitor]]
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[[Category: Membrane]]
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[[Category: Ns3 protease domain]]
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[[Category: Nucleotide-binding]]
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[[Category: Rna replication]]
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[[Category: Serine protease]]
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[[Category: Transmembrane]]
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[[Category: Viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 12:09:19 2010''

Revision as of 08:58, 27 October 2010

Image:3knx.jpg

Template:STRUCTURE 3knx

HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor

Template:ABSTRACT PUBMED 19102654

About this Structure

3KNX is a 4 chains structure with sequences from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.

Reference

  • Venkatraman S, Velazquez F, Wu W, Blackman M, Chen KX, Bogen S, Nair L, Tong X, Chase R, Hart A, Agrawal S, Pichardo J, Prongay A, Cheng KC, Girijavallabhan V, Piwinski J, Shih NY, Njoroge FG. Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease. J Med Chem. 2009 Jan 22;52(2):336-46. PMID:19102654 doi:10.1021/jm800940u

Page seeded by OCA on Wed Oct 27 12:09:19 2010

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OCA

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