Neuroligin
From Proteopedia
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{{STRUCTURE_3be8| PDB=3be8 | SIZE=300| SCENE=Neuroligin/Cv/1 |right|CAPTION=Neuroligin [[3be8]] }} | {{STRUCTURE_3be8| PDB=3be8 | SIZE=300| SCENE=Neuroligin/Cv/1 |right|CAPTION=Neuroligin [[3be8]] }} | ||
| - | [[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic | + | [[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, ''i.e.'' the crystal structure of human Neuroligin ([[3be8]]). |
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
Revision as of 10:49, 27 October 2010
Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, i.e. the crystal structure of human Neuroligin (3be8).
3D Structures of Neuroligin
NLGN
3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat
NLGN+NRXN
2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Pascale Marchot, Jaime Prilusky, David Canner
