3mar

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3mar.jpg|left|200px]]
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The entry 3mar is ON HOLD until Paper Publication
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{{STRUCTURE_3mar| PDB=3mar | SCENE= }}
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Authors: Yang, B., Peng, Y., Ding, J.
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===Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP===
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Description: Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 09:36:41 2010''
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{{ABSTRACT_PUBMED_20975740}}
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==About this Structure==
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3MAR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAR OCA].
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==Reference==
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<ref group="xtra">PMID:20975740</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Ding, J.]]
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[[Category: Peng, Y.]]
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[[Category: Yang, B.]]
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[[Category: Isocitrate dehydrogenase]]
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[[Category: Nicotinamide adenine dinucleotide phosphate]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:48:46 2010''

Revision as of 03:37, 10 November 2010

Image:3mar.jpg

Template:STRUCTURE 3mar

Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP

Template:ABSTRACT PUBMED 20975740

About this Structure

3MAR is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yang B, Zhong C, Peng Y, Lai Z, Ding J. Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res. 2010 Nov;20(11):1188-200. Epub 2010 Oct 26. PMID:20975740 doi:10.1038/cr.2010.145

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