1nlr
From Proteopedia
(New page: 200px<br /> <applet load="1nlr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nlr, resolution 1.75Å" /> '''ENDO-1,4-BETA-GLUCA...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1NLR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NLR OCA]]. | + | 1NLR is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]]. Active as [[http://en.wikipedia.org/wiki/Cellulase Cellulase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Structure known Active Sites: GAB and NF. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NLR OCA]]. |
==Reference== | ==Reference== | ||
The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution., Sulzenbacher G, Shareck F, Morosoli R, Dupont C, Davies GJ, Biochemistry. 1997 Dec 23;36(51):16032-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9440876 9440876] | The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution., Sulzenbacher G, Shareck F, Morosoli R, Dupont C, Davies GJ, Biochemistry. 1997 Dec 23;36(51):16032-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9440876 9440876] | ||
| + | [[Category: Cellulase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Streptomyces lividans]] | [[Category: Streptomyces lividans]] | ||
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[[Category: glycosyl hydrolase]] | [[Category: glycosyl hydrolase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:08:51 2007'' |
Revision as of 09:04, 30 October 2007
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ENDO-1,4-BETA-GLUCANASE CELB2, CELLULASE, NATIVE STRUCTURE
Overview
Cellulases are the glycoside hydrolases responsible for the enzymatic, breakdown of the structural plant polymer cellulose. Together with, xylanases they counteract the lmitless accumulation of plant biomass in, nature and are of considerable fundamental and biotechnological interest., Endoglucanase CelB from Streptomyces lividans performs hydrolysis of the, beta-1,4-glycosidic bonds of cellulose, with net retention of anomeric, configuration. The enzyme is a member of glycoside hydrolase family 12, [Henrissat, B., and Bairoch, A. (1996) Biochem. J. 316, 695-696], which, had previously eluded detailed structural analysis. A truncated, but, cataytically competent form of CelB, locking the flexible linker region, and cellulose-binding domain, has been constructed and overexpressed in a, S. ... [(full description)]
About this Structure
1NLR is a [Single protein] structure of sequence from [Streptomyces lividans]. Active as [Cellulase], with EC number [3.2.1.4]. Structure known Active Sites: GAB and NF. Full crystallographic information is available from [OCA].
Reference
The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution., Sulzenbacher G, Shareck F, Morosoli R, Dupont C, Davies GJ, Biochemistry. 1997 Dec 23;36(51):16032-9. PMID:9440876
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