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3n2u
From Proteopedia
(Difference between revisions)
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| + | {{STRUCTURE_3n2u| PDB=3n2u | SCENE= }} | ||
| - | + | ===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(4-methoxy-N(2-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)ethyl)phenylsulfonamido)acetamide=== | |
| - | Description: Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(4-methoxy-N(2-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)ethyl)phenylsulfonamido)acetamide | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20965620}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20965620 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20965620}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3N2U is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2U OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20965620</ref><ref group="xtra">PMID:17269766</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Macrophage elastase]] | ||
| + | [[Category: Calderone, V.]] | ||
| + | [[Category: Elastase]] | ||
| + | [[Category: Extracellular matrix]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Matrix metalloproteinase]] | ||
| + | [[Category: Metal-inding]] | ||
| + | [[Category: Metallo elastase]] | ||
| + | [[Category: Metalloprotease]] | ||
| + | [[Category: Mmp12]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Secreted]] | ||
| + | [[Category: Zymogen]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:49:24 2010'' | ||
Revision as of 03:38, 10 November 2010
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(4-methoxy-N(2-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)ethyl)phenylsulfonamido)acetamide
Template:ABSTRACT PUBMED 20965620
About this Structure
3N2U is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Attolino E, Calderone V, Dragoni E, Fragai M, Richichi B, Luchinat C, Nativi C. Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem. 2010 Oct 19. PMID:20965620 doi:10.1016/j.ejmech.2010.09.057
- Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
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