2qxs

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===Crystal Structure of Antagonizing Mutant 536S of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Raloxifene===
===Crystal Structure of Antagonizing Mutant 536S of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Raloxifene===
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{{ABSTRACT_PUBMED_20924370}}
==About this Structure==
==About this Structure==
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2QXS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QXS OCA].
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2QXS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QXS OCA].
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==Reference==
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<ref group="xtra">PMID:20924370</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bruning, J B.]]
[[Category: Bruning, J B.]]
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[[Category: Nettles, K W.]]
[[Category: Nettles, K W.]]
[[Category: Nowak, J.]]
[[Category: Nowak, J.]]
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[[Category: Alternative splicing]]
 
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Lipid-binding]]
[[Category: Lipid-binding]]
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[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
 
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
[[Category: Receptor]]
[[Category: Receptor]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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[[Category: Zinc]]
 
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:21:57 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:53:35 2010''

Revision as of 03:42, 10 November 2010

Template:STRUCTURE 2qxs

Crystal Structure of Antagonizing Mutant 536S of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Raloxifene

Template:ABSTRACT PUBMED 20924370

About this Structure

2QXS is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bruning JB, Parent AA, Gil G, Zhao M, Nowak J, Pace MC, Smith CL, Afonine PV, Adams PD, Katzenellenbogen JA, Nettles KW. Coupling of receptor conformation and ligand orientation determine graded activity. Nat Chem Biol. 2010 Nov;6(11):837-43. Epub 2010 Oct 10. PMID:20924370 doi:10.1038/nchembio.451

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