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Leucine-rich repeat

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==Additional Literature==
==Additional Literature==
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<ref group="xtra">PMID: 11751054/ref><ref group="xtra">PMID: 17192264</ref><ref group="xtra">PMID: 17517123</ref><ref group="xtra">PMID: 16231091</ref><ref group="xtra">PMID: 11967365</ref><references group="xtra"/>
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<ref group="xtra">PMID: 11751054</ref><ref group="xtra">PMID: 17192264</ref><ref group="xtra">PMID: 17517123</ref><ref group="xtra">PMID: 16231091</ref><ref group="xtra">PMID: 11967365</ref><references group="xtra"/>

Revision as of 02:49, 19 November 2010

A large family of over 60,000 horseshoe- or arc-shaped proteins named for a repeated motif that always contains leucine.[1]

PDB ID 3e6j

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Lamprey Variable Lymphocyte Receptor (3e6j), resolution 1.67Å ()
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Articles in Proteopedia concerning Leucine-rich repeat proteins include:



PDB ID 1xwd

Drag the structure with the mouse to rotate
1xwd, resolution 2.92Å ()
Ligands: , ,
Gene: CGA (Homo sapiens), FSHB (Homo sapiens), FSHR (Homo sapiens)
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


To view automatically seeded indices concerning Leucine-rich repeat proteins, see:

References

  1. ↑ Matsushima N, Miyashita H, Mikami T, Kuroki Y. A nested leucine rich repeat (LRR) domain: the precursor of LRRs is a ten or eleven residue motif. BMC Microbiol. 2010 Sep 9;10:235. PMID:20825685 doi:10.1186/1471-2180-10-235

See Also

Additional Literature

  • Kobe B, Kajava AV. The leucine-rich repeat as a protein recognition motif. Curr Opin Struct Biol. 2001 Dec;11(6):725-32. PMID:11751054
  • Kim HM, Oh SC, Lim KJ, Kasamatsu J, Heo JY, Park BS, Lee H, Yoo OJ, Kasahara M, Lee JO. Structural diversity of the hagfish variable lymphocyte receptors. J Biol Chem. 2007 Mar 2;282(9):6726-32. Epub 2006 Dec 27. PMID:17192264 doi:10.1074/jbc.M608471200
  • Matsushima N, Tanaka T, Enkhbayar P, Mikami T, Taga M, Yamada K, Kuroki Y. Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors. BMC Genomics. 2007 May 21;8:124. PMID:17517123 doi:10.1186/1471-2164-8-124
  • Matsushima N, Tachi N, Kuroki Y, Enkhbayar P, Osaki M, Kamiya M, Kretsinger RH. Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases. Cell Mol Life Sci. 2005 Dec;62(23):2771-91. PMID:16231091 doi:10.1007/s00018-005-5187-z
  • Kajava AV, Kobe B. Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information. Protein Sci. 2002 May;11(5):1082-90. PMID:11967365 doi:10.1110/ps.4010102

Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Jaime Prilusky, Michal Harel

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