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Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding <ref>PMDI 8415649</ref>
Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding <ref>PMDI 8415649</ref>
[http://www.pubmed.com publicaciones medicas] <references/>
[http://www.pubmed.com publicaciones medicas] <references/>
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escena copiada del señor scene='User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe/1hho_bio/1'/>

Revision as of 13:42, 23 November 2010

Estructura acetilcolinesterasa

acelit colinesterasa

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1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor.

It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease.

ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 ( ).


Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding [1]

publicaciones medicas
  1. PMDI 8415649

escena copiada del señor scene='User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe/1hho_bio/1'/>

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