1kyh
From Proteopedia
(New page: 200px<br /><applet load="1kyh" size="450" color="white" frame="true" align="right" spinBox="true" caption="1kyh, resolution 1.60Å" /> '''Structure of Bacillu...) |
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| - | [[Image:1kyh.gif|left|200px]]<br /><applet load="1kyh" size=" | + | [[Image:1kyh.gif|left|200px]]<br /><applet load="1kyh" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1kyh, resolution 1.60Å" /> | caption="1kyh, resolution 1.60Å" /> | ||
'''Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase'''<br /> | '''Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1KYH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http:// | + | 1KYH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KYH OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Collart, F.]] | [[Category: Collart, F.]] | ||
| - | [[Category: | + | [[Category: Dementieva, I.]] |
[[Category: Joachimiak, A.]] | [[Category: Joachimiak, A.]] | ||
[[Category: MCSG, Midwest.Center.for.Structural.Genomics.]] | [[Category: MCSG, Midwest.Center.for.Structural.Genomics.]] | ||
[[Category: Vinokour, E.]] | [[Category: Vinokour, E.]] | ||
| - | [[Category: Zhang, R | + | [[Category: Zhang, R.]] |
[[Category: mcsg]] | [[Category: mcsg]] | ||
[[Category: midwest center for structural genomics]] | [[Category: midwest center for structural genomics]] | ||
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[[Category: psi]] | [[Category: psi]] | ||
[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| + | [[Category: unknown function]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 11:49:02 2008'' |
Revision as of 09:49, 23 January 2008
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Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase
Overview
We determined the 1.6-A resolution crystal structure of a conserved, hypothetical 29.9-kDa protein from the SIGY-CYDD intergenic region encoded, by a Bacillus subtilis open reading frame in the YXKO locus. YXKO, homologues are broadly distributed and are by and large described as, proteins with unknown function. The YXKO protein has an alpha/beta fold, and shows high structural homology to the members of a ribokinase-like, superfamily. However, YXKO is the only member of this superfamily known to, form tetramers. Putative binding sites for adenosine triphosphate (ATP), a, substrate, and Mg(2+)-binding sites were revealed in the structure of the, protein, based on high structural similarity to ATP-dependent members of, the superfamily. Two adjacent monomers contribute residues to the active, site. The crystal structure provides valuable information about the YXKO, protein's tertiary and quaternary structure, the biochemical function of, YXKO and its homologues, and the evolution of its ribokinase-like, superfamily.
About this Structure
1KYH is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase., Zhang RG, Grembecka J, Vinokour E, Collart F, Dementieva I, Minor W, Joachimiak A, J Struct Biol. 2002 Sep;139(3):161-70. PMID:12457846
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