Beta secretase
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
'''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''', is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention. | '''β-Secretase''', also known as '''BACE''' ('''β'''-site of '''A'''myloid precursor protein '''C'''leaving '''E'''nzyme) and '''Memapsin 2''', is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention. | ||
| + | |||
| + | _TOC_ | ||
==Structure of Beta Secretase== | ==Structure of Beta Secretase== | ||
==Alzheimer's Disease== | ==Alzheimer's Disease== | ||
==Inhibition of Beta Secretase== | ==Inhibition of Beta Secretase== | ||
Revision as of 07:28, 29 November 2010
|
β-Secretase, also known as BACE (β-site of Amyloid precursor protein Cleaving Enzyme) and Memapsin 2, is an aspartyl protease found in humans. β-Secretase plays an important role in the development of Alzheimer's disease. This has made β-secretase a therapeutic target for pharmacological intervention.
_TOC_
Structure of Beta Secretase
Alzheimer's Disease
Inhibition of Beta Secretase
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Daniel Santos, Jaime Prilusky, Joel L. Sussman, David Canner
