HIV Protease Resistance

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Line 6: Line 6:
!Inhibitor/Mutation Site
!Inhibitor/Mutation Site
!L10
!L10
 +
!V11
!I13
!I13
!G16
!G16
Line 45: Line 46:
![[Ritonavir]]
![[Ritonavir]]
!I,R,V
!I,R,V
 +
!-
!-
!-
!-
!-
Line 84: Line 86:
![[Indinavir]]
![[Indinavir]]
!I,R,V
!I,R,V
 +
!-
!-
!-
!-
!-
Line 123: Line 126:
![[Saquinavir]]
![[Saquinavir]]
!I,R,V
!I,R,V
 +
!-
!-
!-
!-
!-
Line 162: Line 166:
![[Nelfinavir]]
![[Nelfinavir]]
!F,I
!F,I
 +
!-
!-
!-
!-
!-
Line 201: Line 206:
![[Amprenavir]]
![[Amprenavir]]
!F,I,R,V
!F,I,R,V
 +
!-
!-
!-
!-
!-
Line 240: Line 246:
![[Atazanavir]]
![[Atazanavir]]
!I,F,V
!I,F,V
 +
!-
!-
!-
!-
!-
Line 279: Line 286:
![[Lopinavir]] & [[Ritonavir]]
![[Lopinavir]] & [[Ritonavir]]
!F,I,R,V
!F,I,R,V
 +
!-
!-
!-
!-
!-
Line 356: Line 364:
!Visualize
!Visualize
![[Darunavir]] & [[Ritonavir]]
![[Darunavir]] & [[Ritonavir]]
-
!L10
+
!-
 +
!I
!I13
!I13
!G16
!G16

Revision as of 12:59, 2 December 2010

Resistance Mutations
Visualize Inhibitor/Mutation Site L10 V11 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Ritonavir I,R,V - - - M,R - - I F - - I - I,L - - - - V,L - - - - - V,T - - - I A,F,T,S - V - - - M -
Indinavir I,R,V - - - M,R I - I - - - I - I,L - - - - V - - - - - V,T S,A - - I A,F,T V - - - M -
Visualize Saquinavir I,R,V - - - - - - - - - - - - - - V - - V,L - - - - - V,T S - - I A - V - - - M -
Visualize Nelfinavir F,I - - - - - N - - - - I - I,L - - - - - - - - - - V,T - - - I A,F,T,S - V - D,S M -
Visualize Amprenavir F,I,R,V - - - - - - I - - - - - I,L V - V - L,V,M - - - - - - S - - - - - V - - - M -
Visualize Atazanavir I,F,V - - - R,M,I I - I I,F,V - - I,L,V - I - V L - L - - - - - V C,S,T,A - - - A - V - S - M -
Visualize Lopinavir & Ritonavir F,I,R,V - - - M,R I - I F - - - - I,L V,A - V L V,L,A,M,T,S - - P - - V,T S - V - A,F,T,S - V - - - M
Visualize Atazanavir & Ritonavir I,F,V,C - E R,M,I,T,V I - I I,F,V Q - I,L,V - I,L - V V L,Y L,V,M,T,A E V - L,M,V - V,I,T,L C,S,T,A - - - A,T,F,I - V V S - M L,M
Visualize Darunavir & Ritonavir - I I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Fosamprenavir & Ritonavir L10 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Indinavir & Ritonavir L10 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Saquinavir & Ritonavir L10 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93
Visualize Tipranavir & Ritonavir L10 I13 G16 K20 L24 D30 V32 L33 E34 E35 M36 K43 M46 I47 G48 I50 F53 I54 D60 I62 L63 I64 H69 A71 G73 T74 L76 V77 V82 N83 I84 I85 N88 L89 L90 I93

Proteopedia Page Contributors and Editors (what is this?)

David Canner

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