HIV Protease Resistance

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Revision as of 13:16, 2 December 2010

Resistance Mutations
Visualize	Inhibitor/Mutation Site	L10	V11	I13	G16	K20	L24	D30	V32	L33	E34	E35	M36	K43	M46	I47	G48	I50	F53	I54	D60	I62	L63	I64	H69	A71	G73	T74	L76	V77	V82	N83	I84	I85	N88	L89	L90	I93
Visualize	Ritonavir	I,R,V	-	-	-	M,R	-	-	I	F	-	-	I	-	I,L	-	-	-	-	V,L	QQQ	-	-	-	-	-	V,T	-	-	-	I	A,F,T,S	-	V	-	-	-	M	-
	Indinavir	I,R,V	-	-	-	M,R	I	-	I	-	-	-	I	-	I,L	-	-	-	-	V	-	-	-	-	-	V,T	S,A	-	-	I	A,F,T		V	-	-	-	M	-
Visualize	Saquinavir	I,R,V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	V	-	-	V,L	QQQ	-	-	-	-	-	V,T	S	-	-	I	A	-	V	-	-	-	M	-
Visualize	Nelfinavir	F,I	-	-	-	-	-	N	-	-	-	-	I	-	I,L	QQQ	-	-	-	-	-	-	-	-	-	-	V,T	-	-	-	I	A,F,T,S	-	V	-	D,S		M	-
Visualize	Amprenavir	F,I,R,V	-	-	-	-	-	-	I	-	-	-	-	-	I,L	V	-	V	-	L,V,M	QQQ	-	-	-	-	-	-	S	-	-	-	-	-	V	-	-	-	M	-
Visualize	Atazanavir	I,F,V	-	-	-	R,M,I	I	-	I	I,F,V	-	-	I,L,V	-	I	-	V	L	QQQ	-	L	-	-	-	-	-	V	C,S,T,A	-	-	-	A	-	V	-	S	-	M	-
Visualize	Lopinavir & Ritonavir	F,I,R,V	-	-	-	M,R	I	-	I	F	-	-	-	-	I,L	V,A	-	V	L	V,L,A,M,T,S	-	-	P	-	-	V,T	S	-	V	-	A,F,T,S	-	V	-	-	-	M
Visualize	Atazanavir & Ritonavir	I,F,V,C	-	-	E	R,M,I,T,V	I	-	I	I,F,V	Q	-	I,L,V	-	I,L	QQQ	-	V	V	L,Y	L,V,M,T,A	E	V	-	L,M,V	-	V,I,T,L	C,S,T,A	-	-	-	A,T,F,I	-	V	V	S	-	M	L,M
Visualize	Darunavir & Ritonavir	-	I	-	-	-	-	-	I	F	-	-	-	-	-	V	-	V	-	M,L	QQQ	-	-	-	-	-	-	-	P	V	-	-	-	V	-	-	V	-	-
Visualize	Fosamprenavir & Ritonavir	F,I,R,V	-	-	-	-	-	-	I	-	-	-	-	-	I,L	V	-	V	-	L,V,M	QQQ	-	-	-	-	-	-	S	-	V	-	A,F,S,T	-	V	-	-	-	M	-
Visualize	Indinavir & Ritonavir	I,R,V	-	-	-	M,R	I	-	I	-	-	-	I	-	I,L	QQQ	-	-	-	-	V	-	-	-	-	-	V,T	S,A	-	V	I	A,F,T	-	V	-	-	-	M	-
Visualize	Saquinavir & Ritonavir	I,R,V	-	-	-	-	I	-	-	-	-	-	-	-	-	-	V	-	-	V,L	QQQ	-	V	-	-	-	V,T	S	-	-	I	A,F,T,S	-	V	-	-	-	M	-
Visualize	Tipranavir & Ritonavir	V	-	V	-	M,R	-	-	-	F	-	G	I	T	L	V	QQQ	-	-	-	A,M,V	E	-	-	-	-	K	-	-	P	-	-	L,T	D	V	-	-	-	M	-