Phl p 2

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Revision as of 17:28, 2 December 2010

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Immune system

The immune system is the body's way of protecting itself from foreign and potentially harmful microbes such as viruses and bacteria. When an unknown substance enters the body the immune system responds with a cascade of reactions which begin with identification of the microbe and hopefully ends with the neutralization of the pathogen. The identification and recognition of a pathogen however is a tricky process as the immune system must be able to differentiate between its own cells and foreign ones. The inability of the immune system to differentiate between foreign and native cells is potentially dangerous as it could lead to autoimmune diseases which can vary in severity from eczema to lupus. The responsibility of identifying pathogens is put on small glycoproteins called antibodies.

Antibodies

Image:Immunoglobulin.jpg Image:Antibody_basic_structure.gif

Type I Hypersensitivity

Image:Allergic_reactions.jpg

Hypersensitivity mechanism

Image:Plasma_cell_and_mast_cell_with_antibodies.jpg Image:Histamine_release_degranulation.jpg Image:ANTIGEN_IMAGE_PROTEOPEDIA.JPEG

Phl p 2 and huMab2

Image:Phlp2_huMab2_direct_contacts.jpg


Proteopedia Page Contributors and Editors (what is this?)

Kirsten Cheng, Alexander Berchansky, Michal Harel

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