Tol
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | The Tol system, also known as Tol-Pal, is a multiprotein complex in the cell envelope of many | + | The Tol system, also known as Tol-Pal, is a multiprotein complex found in the cell envelope of many gram-negative bacteria. It contains 7 proteins ([[TolQ]], [[TolR]], [[TolA]], [[TolB]], [[Pal]], [[YbgF]], [[YbgC]]) organised into two operons. |
[[Image:Tol Operon.jpg]] | [[Image:Tol Operon.jpg]] | ||
Revision as of 16:49, 3 December 2010
The Tol system, also known as Tol-Pal, is a multiprotein complex found in the cell envelope of many gram-negative bacteria. It contains 7 proteins (TolQ, TolR, TolA, TolB, Pal, YbgF, YbgC) organised into two operons.
Contents |
Structure
Function
Regulation
It has been shown that the regulation of Tol genes is linked to the cell envelope stability. [1] In studies with E. coli, the tol-pal genes have been induced by RcsC in response to cell envelope stress. [2] RcsC is a transmembrane sensor kinase, and along with the cytoplasmic response regulator RcsB, makes up the RcsBC regulatory system. [3] RcsBC is involved in the regulation of cps genes which code for the biosynthsis machinery of a major componant for the capsula, cholanic acid.
