3ns9

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ns9.jpg|left|200px]]
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The entry 3ns9 is ON HOLD until Paper Publication
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{{STRUCTURE_3ns9| PDB=3ns9 | SCENE= }}
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Authors: Hazel, P., Freemont, P.S.
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===Crystal structure of CDK2 in complex with inhibitor BS-194===
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Description: Crystal structure of CDK2 in complex with inhibitor BS-194
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 05:46:37 2010''
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{{ABSTRACT_PUBMED_21080703}}
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==About this Structure==
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3NS9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NS9 OCA].
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==Reference==
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<ref group="xtra">PMID:21080703</ref><references group="xtra"/>
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[[Category: Cyclin-dependent kinase]]
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[[Category: Homo sapiens]]
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[[Category: Freemont, P S.]]
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[[Category: Hazel, P.]]
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[[Category: Protein kinase]]
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[[Category: Transferase-transferase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:50:47 2010''

Revision as of 08:38, 8 December 2010

Image:3ns9.jpg

Template:STRUCTURE 3ns9

Crystal structure of CDK2 in complex with inhibitor BS-194

Template:ABSTRACT PUBMED 21080703

About this Structure

3NS9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, Snyder JP, Liotta DC, Freemont PS, Aboagye EO, Coombes RC, Barrett AG, Ali S. A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration. J Med Chem. 2010 Nov 16. PMID:21080703 doi:10.1021/jm100732t

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