2xti

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2xti.jpg|left|200px]]
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The entry 2xti is ON HOLD until Paper Publication
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{{STRUCTURE_2xti| PDB=2xti | SCENE= }}
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Authors: Crepin, T., Haertlein, M., Kron, M., Cusack, S.
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===ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH ATP:MG AND L-ASP-BETA-NOH ADENYLATE:PPI:MG===
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Description: Asparaginyl-tRNA synthetase from Brugia malayi complexed with ATP:Mg and L-Asp-beta-NOH adenylate:PPi:Mg
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:50:28 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 21134380 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21134380}}
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==About this Structure==
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2XTI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Brugia_malayi Brugia malayi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTI OCA].
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==Reference==
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<ref group="xtra">PMID:21134380</ref><ref group="xtra">PMID:16645791</ref><references group="xtra"/>
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[[Category: Brugia malayi]]
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[[Category: Leucine--tRNA ligase]]
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[[Category: Crepin, T.]]
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[[Category: Cusack, S.]]
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[[Category: Haertlein, M.]]
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[[Category: Kron, M.]]
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[[Category: Atp-binding]]
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[[Category: Filariasis]]
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[[Category: Ligase]]
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[[Category: Protein biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:39:35 2010''

Revision as of 05:27, 15 December 2010

Image:2xti.jpg

Template:STRUCTURE 2xti

ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH ATP:MG AND L-ASP-BETA-NOH ADENYLATE:PPI:MG

Template:ABSTRACT PUBMED 21134380

About this Structure

2XTI is a 2 chains structure with sequences from Brugia malayi. Full crystallographic information is available from OCA.

Reference

  • Crepin T, Peterson F, Haertlein M, Jensen D, Wang C, Cusack S, Kron M. A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase. J Mol Biol. 2010 Dec 4. PMID:21134380 doi:10.1016/j.jmb.2010.11.049
  • Sukuru SC, Crepin T, Milev Y, Marsh LC, Hill JB, Anderson RJ, Morris JC, Rohatgi A, O'Mahony G, Grotli M, Danel F, Page MG, Hartlein M, Cusack S, Kron MA, Kuhn LA. Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change. J Comput Aided Mol Des. 2006 Mar;20(3):159-78. Epub 2006 Apr 28. PMID:16645791 doi:10.1007/s10822-006-9043-5

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