3lok

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lok.jpg|left|200px]]
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The entry 3lok is ON HOLD until Paper Publication
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{{STRUCTURE_3lok| PDB=3lok | SCENE= }}
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Authors: Gruetter, C., Rode, H.B., Rauh, D.
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===Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393===
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Description: Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 13:13:32 2010''
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{{ABSTRACT_PUBMED_21080395}}
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==About this Structure==
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3LOK is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOK OCA].
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==Reference==
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<ref group="xtra">PMID:21080395</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Gruetter, C.]]
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[[Category: Rauh, D.]]
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[[Category: Rode, H B.]]
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[[Category: Atp-binding]]
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[[Category: Covalent inhibitor]]
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[[Category: Drug resistance]]
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[[Category: Irreversible inhibitor]]
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[[Category: Kinase]]
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[[Category: Lipoprotein]]
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[[Category: Myristate]]
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[[Category: Nucleotide-binding]]
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[[Category: Pd168393]]
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[[Category: Phosphoprotein]]
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[[Category: Proto-oncogene]]
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[[Category: Sh2 domain]]
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[[Category: Sh3 domain]]
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[[Category: Src kinase domain]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:53:27 2010''

Revision as of 06:40, 22 December 2010

Image:3lok.jpg

Template:STRUCTURE 3lok

Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393

Template:ABSTRACT PUBMED 21080395

About this Structure

3LOK is a 2 chains structure with sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Kluter S, Simard JR, Rode HB, Grutter C, Pawar V, Raaijmakers HC, Barf TA, Rabiller M, van Otterlo WA, Rauh D. Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance. Chembiochem. 2010 Dec 10;11(18):2557-66. PMID:21080395 doi:10.1002/cbic.201000352

Page seeded by OCA on Wed Dec 22 09:53:27 2010

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