3pup

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(New page: '''Unreleased structure''' The entry 3pup is ON HOLD Authors: Filippakopoulos, P., Kraling, K., Essen, L.O., Meggers, E., Knapp, S. Description: Structure of Glycogen Synthase Kinase 3...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3pup.jpg|left|200px]]
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The entry 3pup is ON HOLD
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{{STRUCTURE_3pup| PDB=3pup | SCENE= }}
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Authors: Filippakopoulos, P., Kraling, K., Essen, L.O., Meggers, E., Knapp, S.
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===Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)===
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Description: Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:25:43 2010''
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==About this Structure==
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3PUP is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PUP OCA].
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==Reference==
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<ref group="xtra">PMID:18973295</ref><ref group="xtra">PMID:19035373</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Essen, L O.]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Knapp, S.]]
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[[Category: Kraling, K.]]
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[[Category: Meggers, E.]]
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[[Category: Atp-binding]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Ruthenium glycogen synthase kinase picomolar]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Wnt signaling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 10:02:51 2010''

Revision as of 06:50, 22 December 2010

Image:3pup.jpg

Template:STRUCTURE 3pup

Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1)

About this Structure

3PUP is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. J Am Chem Soc. 2008 Nov 26;130(47):15764-5. PMID:18973295 doi:10.1021/ja805555a
  • Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem. 2008 Dec 15;9(18):2933-6. PMID:19035373 doi:10.1002/cbic.200800489

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