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Neuroligin
From Proteopedia
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[[3b3q]] - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain<br /> | [[3b3q]] - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain<br /> | ||
[[3biw]] - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain<br /> | [[3biw]] - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain<br /> | ||
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Revision as of 03:29, 23 December 2010
Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. The NLGN family contains 4 members which are numbered 1 to 4. The images at the left and at the right correspond to one representative NLGN, i.e. the crystal structure of human Neuroligin (3be8).
3D Structures of Neuroligin
NLGN
3bl8 - mNLGN-2 cholinesterase domain – mouse
3be8 - hNLGN-4 cholinesterase domain – human
3bix - rNLGN-1 cholinesterase domain - rat
NLGN+NRXN
2xb6, 2wqz – hNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3b3q - mNLGN-4 cholinesterase domain+NRXN-1β LNS domain
3biw - rNLGN-1 cholinesterase domain+NRXN-1β LNS domain
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Pascale Marchot, Jaime Prilusky, David Canner
