This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2zvt
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2zvt.png|left|200px]] | [[Image:2zvt.png|left|200px]] | ||
| Line 18: | Line 17: | ||
--> | --> | ||
{{ABSTRACT_PUBMED_19101554}} | {{ABSTRACT_PUBMED_19101554}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Insulin resistance, severe, digenic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Lipodystrophy, familial partial, type 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, severe OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Obesity, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Diabetes, type 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]], Glioblastoma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601487 601487]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2zvt]] is a 2 chain structure of [[Peroxisome Proliferator-Activated Receptors]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVT OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Peroxisome Proliferator-Activated Receptors]] | ||
==Reference== | ==Reference== | ||
| Line 48: | Line 47: | ||
[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:23:20 2010'' | ||
Revision as of 08:06, 26 December 2010
Contents |
Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
Template:ABSTRACT PUBMED 19101554
About this Structure
2zvt is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Waku T, Shiraki T, Oyama T, Morikawa K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 2009 Jan 22;583(2):320-4. Epub 2008 Dec 26. PMID:19101554 doi:10.1016/j.febslet.2008.12.017
Categories: Homo sapiens | Morikawa, K. | Oyama, T. | Shiraki, T. | Waku, T. | Activator | Alternative splicing | Anti parallel helix sandwich | Diabetes mellitus | Disease mutation | Dna-binding | Metal-binding | Nucleus | Obesity | Phosphoprotein | Polymorphism | Receptor | Transcription | Transcription regulation | Zinc | Zinc-finger
