Template:STRUCTURE 1dq8

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Revision as of 08:15, 26 December 2010

1dq8, resolution 2.10Å ()

Sites:

, , , , , , , , and

Ligands:

, ,

Activity:

Hydroxymethylglutaryl-CoA reductase (NADPH), with EC number 1.1.1.34

Structural annotation:
Resources:	CATH : 1Dq8A03, 1Dq8A02, 1Dq8A01, 1Dq8B02, 1Dq8B01, 1Dq8B03, 1Dq8C02, 1Dq8C01, 1Dq8C03, 1Dq8D03, 1Dq8D02, 1Dq8D01 InterPro : Ipr009023, Ipr000731, Ipr002202, Ipr004816, Ipr004554, Ipr009029 Pfam : PF00368 SCOP : d1dq8a4, d1dq8a1, d1dq8b4, d1dq8b1, d1dq8c1, d1dq8c4, d1dq8d1, d1dq8d4 UniProt : P04035

Functional annotation:
Cellular component:	membrane fraction endoplasmic reticulum endoplasmic reticulum membrane membrane peroxisome integral to membrane
Biological process:	germ cell migration lipid metabolic process cholesterol biosynthetic process gonad development sterol biosynthetic process cholesterol metabolic process lipid biosynthetic process biosynthetic process steroid biosynthetic process
Molecular function:	oxidoreductase activity hydroxymethylglutaryl-CoA reductase (NADPH) activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1dq8"

@@ Line 1: / Line 1: @@
 {{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1dq8]], resolution 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1dq8]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|SITE= <scene name='pdbsite=AC1:Binding+Site+For+Residue+Coa+A+100'>AC1</scene>, <scene name='pdbsite=AC2:Binding+Site+For+Residue+Coa+B+101'>AC2</scene>, <scene name='pdbsite=AC3:Binding+Site+For+Residue+Coa+C+102'>AC3</scene>, <scene name='pdbsite=AC4:Binding+Site+For+Residue+Coa+D+103'>AC4</scene>, <scene name='pdbsite=AC5:Binding+Site+For+Residue+Mah+A+200'>AC5</scene>, <scene name='pdbsite=AC6:Binding+Site+For+Residue+Mah+B+201'>AC6</scene>, <scene name='pdbsite=AC7:Binding+Site+For+Residue+Mah+D+202'>AC7</scene>, <scene name='pdbsite=AC8:Binding+Site+For+Residue+Mah+D+203'>AC8</scene>, <scene name='pdbsite=AC9:Binding+Site+For+Residue+Dtt+C+301'>AC9</scene> and <scene name='pdbsite=BC1:Binding+Site+For+Residue+Dtt+B+302'>BC1</scene>
 |LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=MAH:3-HYDROXY-3-METHYL-GLUTARIC+ACID'>MAH</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00643 HMG-CoA_reductase_classI]</span>
 |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq8 OCA], [http://www.ebi.ac.uk/pdbsum/1dq8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dq8 RCSB]</span>
 |FUNCTION={{GO|id=GO:0016491 | text = oxidoreductase activity}}{{GO|id=GO:0004420 | text = hydroxymethylglutaryl-CoA reductase (NADPH) activity}}
@@ Line 9: / Line 9: @@
 |COMPONENT={{GO|id=GO:0005624 | text = membrane fraction}}{{GO|id=GO:0005783 | text = endoplasmic reticulum}}{{GO|id=GO:0005789 | text = endoplasmic reticulum membrane}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005777 | text = peroxisome}}{{GO|id=GO:0016021 | text = integral to membrane}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8A03 1Dq8A03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8A02 1Dq8A02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8A01 1Dq8A01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8B02 1Dq8B02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8B01 1Dq8B01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8B03 1Dq8B03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8C02 1Dq8C02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8C01 1Dq8C01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8C03 1Dq8C03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8D03 1Dq8D03], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8D02 1Dq8D02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1dq8D01 1Dq8D01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009023 Ipr009023], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000731 Ipr000731], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002202 Ipr002202], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR004816 Ipr004816], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR004554 Ipr004554], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009029 Ipr009029]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00368 PF00368]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=42589 d1dq8a4], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=39368 d1dq8a1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=42590 d1dq8b4], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=39369 d1dq8b1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=39370 d1dq8c1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=42591 d1dq8c4], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=39371 d1dq8d1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=42592 d1dq8d4]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04035 P04035]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=HMGCR HMGCR]</span>
+|uPDB=1DQ8|CONSURF={{!}}-
-|CONSURF={{!}}-
 {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
 {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Template:STRUCTURE 1dq8

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Revision as of 08:15, 26 December 2010

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