1eb6
From Proteopedia
(New page: 200px<br /> <applet load="1eb6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1eb6, resolution 1.00Å" /> '''DEUTEROLYSIN FROM A...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1EB6 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]] with ZN and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.39 3.4.24.39]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1EB6 OCA]]. | + | 1EB6 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Aspergillus_oryzae Aspergillus oryzae]] with ZN and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Deuterolysin Deuterolysin]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.39 3.4.24.39]]. Structure known Active Site: ZN. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1EB6 OCA]]. |
==Reference== | ==Reference== | ||
A quick solution: ab initio structure determination of a 19 kDa metalloproteinase using ACORN., McAuley KE, Jia-Xing Y, Dodson EJ, Lehmbeck J, Ostergaard PR, Wilson KS, Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1571-8. Epub 2001, Oct 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11679721 11679721] | A quick solution: ab initio structure determination of a 19 kDa metalloproteinase using ACORN., McAuley KE, Jia-Xing Y, Dodson EJ, Lehmbeck J, Ostergaard PR, Wilson KS, Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1571-8. Epub 2001, Oct 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11679721 11679721] | ||
| + | [[Category: Aspergillus oryzae]] | ||
| + | [[Category: Deuterolysin]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Dodson, E.J.]] | [[Category: Dodson, E.J.]] | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:19:00 2007'' |
Revision as of 09:14, 30 October 2007
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DEUTEROLYSIN FROM ASPERGILLUS ORYZAE
Overview
A data set from the metalloproteinase deuterolysin was collected at atomic, resolution (1.0 A) with synchrotron radiation. The high resolution allowed, the structure to be solved with the new direct-methods program ACORN using, the coordinates of the Zn atom as a starting point. The phases obtained, from ACORN were of sufficient quality to allow automated building to be, carried out in ARP/wARP. Minimal manual rebuilding of the model was, required and the structure determination was completed using the, maximum-likelihood refinement program REFMAC. The whole process, starting, from the processed and merged data and ending with a refined model, required less than 6 h of computational time.
About this Structure
1EB6 is a [Single protein] structure of sequence from [Aspergillus oryzae] with ZN and EDO as [ligands]. Active as [Deuterolysin], with EC number [3.4.24.39]. Structure known Active Site: ZN. Full crystallographic information is available from [OCA].
Reference
A quick solution: ab initio structure determination of a 19 kDa metalloproteinase using ACORN., McAuley KE, Jia-Xing Y, Dodson EJ, Lehmbeck J, Ostergaard PR, Wilson KS, Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1571-8. Epub 2001, Oct 25. PMID:11679721
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