2rfn
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2rfn" size="450" color="white" frame="true" align="right" spinBox="true" caption="2rfn, resolution 2.50Å" /> '''x-ray structure of ...) |
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- | [[Image:2rfn. | + | [[Image:2rfn.jpg|left|200px]]<br /><applet load="2rfn" size="350" color="white" frame="true" align="right" spinBox="true" |
- | <applet load="2rfn" size=" | + | |
caption="2rfn, resolution 2.50Å" /> | caption="2rfn, resolution 2.50Å" /> | ||
'''x-ray structure of c-Met with inhibitor.'''<br /> | '''x-ray structure of c-Met with inhibitor.'''<br /> | ||
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- | ==Disease== | ||
- | Known diseases associated with this structure: Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]] | ||
==About this Structure== | ==About this Structure== | ||
- | 2RFN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with AM7 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Full crystallographic information is available from [http:// | + | 2RFN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=AM7:'>AM7</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFN OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: tyrosine-protein kinase]] | [[Category: tyrosine-protein kinase]] | ||
- | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:24:26 2008'' |
Revision as of 10:24, 23 January 2008
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x-ray structure of c-Met with inhibitor.
About this Structure
2RFN is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Receptor protein-tyrosine kinase, with EC number 2.7.10.1 Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Jan 23 12:24:26 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Bellon, S.F. | Dussault, I. | Kaplan-Lefko, P. | Moriguchi, J. | Yang, Y. | Zhang, Y. | AM7 | Atp-binding | C-met hgf receptor tyrosine kinse kinase domain | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Proto-oncogene | Transferase | Transmembrane | Tyrosine-protein kinase