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1uzy

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(New page: 200px<br /> <applet load="1uzy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1uzy, resolution 2.00&Aring;" /> '''ERYTHRINA CRYSTAGAL...)
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==About this Structure==
==About this Structure==
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1UZY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]] with CA, MN and EPE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UZY OCA]].
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1UZY is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Eukaryota Eukaryota]] with CA, MN and EPE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UZY OCA]].
==Reference==
==Reference==
Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose., Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR, Glycobiology. 2004 Oct;14(10):923-9. Epub 2004 Jun 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15201215 15201215]
Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose., Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR, Glycobiology. 2004 Oct;14(10):923-9. Epub 2004 Jun 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15201215 15201215]
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[[Category: Eukaryota]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Acharya, K.R.]]
[[Category: Acharya, K.R.]]
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[[Category: lectin]]
[[Category: lectin]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:43:08 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:20:21 2007''

Revision as of 09:15, 30 October 2007

Image:1uzy.gif

1uzy, resolution 2.00Å

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ERYTHRINA CRYSTAGALLI LECTIN

Overview

Erythrina cristagalli lectin (ECL) is a galactose-specific legume lectin., Although its biological function in the legume is unknown, ECL exhibits, hemagglutinating activity in vitro and is mitogenic for T lymphocytes. In, addition, it has been recently shown that ECL forms a novel conjugate when, coupled to a catalytically active derivative of the type A neurotoxin from, Clostridium botulinum, thus providing a therapeutic potential. ECL is, biologically active as a dimer in which each protomer contains a, functional carbohydrate-combining site. The crystal structure of native, ECL was recently reported in complex with lactose and 2'-fucosyllactose., ECL protomers adopt the legume lectin fold but form non-canonical dimers, via the handshake motif as was previously observed for Erythrina, ... [(full description)]

About this Structure

1UZY is a [Single protein] structure of sequence from [Eukaryota] with CA, MN and EPE as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose., Turton K, Natesh R, Thiyagarajan N, Chaddock JA, Acharya KR, Glycobiology. 2004 Oct;14(10):923-9. Epub 2004 Jun 16. PMID:15201215

Page seeded by OCA on Tue Oct 30 11:20:21 2007

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