1nh3
From Proteopedia
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[[Image:1nh3.png|left|200px]] | [[Image:1nh3.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_12533542}} | {{ABSTRACT_PUBMED_12533542}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126420 126420]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nh3]] is a 4 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NH3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Topoisomerase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Dna damage]] | [[Category: Dna damage]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
| + | [[Category: Isomerase/dna complex]] | ||
[[Category: Protein-dna complex]] | [[Category: Protein-dna complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:33:33 2009'' | ||
Revision as of 21:05, 26 December 2010
Contents |
Human Topoisomerase I Ara-C Complex
Template:ABSTRACT PUBMED 12533542
About this Structure
1nh3 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chrencik JE, Burgin AB, Pommier Y, Stewart L, Redinbo MR. Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex. J Biol Chem. 2003 Apr 4;278(14):12461-6. Epub 2003 Jan 17. PMID:12533542 doi:10.1074/jbc.M212930200
