1nh3

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Revision as of 21:05, 26 December 2010

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Template:STRUCTURE 1nh3

Contents 1 Human Topoisomerase I Ara-C Complex 2 About this Structure 3 See Also 4 Reference

Human Topoisomerase I Ara-C Complex

Template:ABSTRACT PUBMED 12533542

About this Structure

1nh3 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Topoisomerase

Reference

• Chrencik JE, Burgin AB, Pommier Y, Stewart L, Redinbo MR. Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex. J Biol Chem. 2003 Apr 4;278(14):12461-6. Epub 2003 Jan 17. PMID:12533542 doi:10.1074/jbc.M212930200