2itz
From Proteopedia
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[[Image:2itz.png|left|200px]] | [[Image:2itz.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2itz]] is a 1 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITZ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
[[Category: Zd1839]] | [[Category: Zd1839]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:20:35 2009'' | ||
Revision as of 21:26, 26 December 2010
Contents |
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH IRESSA
Template:ABSTRACT PUBMED 17349580
About this Structure
2itz is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:http://dx.doi.org/10.1016/j.ccr.2006.12.017
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Boggon, T J. | Eck, M J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C H. | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | Gefitinib | Glycoprotein | Iressa | L858r | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase | Zd1839
