2wi2

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(New page: '''Unreleased structure''' The entry 2wi2 is ON HOLD until Paper Publication Authors: Brough, P.A., Barril, X., Borgognoni, J., Chene, P., Davies, N.G.M., Davis, B., Drysdale, M.J., Dym...)
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'''Unreleased structure'''
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[[Image:2wi2.png|left|200px]]
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The entry 2wi2 is ON HOLD until Paper Publication
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{{STRUCTURE_2wi2| PDB=2wi2 | SCENE= }}
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Authors: Brough, P.A., Barril, X., Borgognoni, J., Chene, P., Davies, N.G.M., Davis, B., Drysdale, M.J., Dymock, B., Eccles, S.A., Garcia-Echeverria, C., Fromont, C., Hayes, A., Hubbard, R.E., Jordan, A., Rugaard-Jensen, M., Massey, A., Merret, A., Padfield, A., Parsons, R., Radimerski, T., Raynaud, F.I., Robertson, A., Roughley, S.D., Schoepfer, J., Simmonite, H., Surgenor, A., Valenti, M., Walls, S., Webb, P., Wood, M., Workman, P., Wright, L.M.
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===ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE===
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Description: Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 16:13:35 2009''
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{{ABSTRACT_PUBMED_19610616}}
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==About this Structure==
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[[2wi2]] is a 2 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WI2 OCA].
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==See Also==
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*[[Heat Shock Proteins]]
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==Reference==
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<ref group="xtra">PMID:19610616</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Barril, X.]]
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[[Category: Borgognoni, J.]]
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[[Category: Brough, P A.]]
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[[Category: Chene, P.]]
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[[Category: Davies, N G.M.]]
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[[Category: Davis, B.]]
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[[Category: Drysdale, M J.]]
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[[Category: Dymock, B.]]
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[[Category: Eccles, S A.]]
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[[Category: Fromont, C.]]
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[[Category: Garcia-Echeverria, C.]]
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[[Category: Hayes, A.]]
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[[Category: Hubbard, R E.]]
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[[Category: Jordan, A M.]]
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[[Category: Massey, A.]]
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[[Category: Merret, A.]]
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[[Category: Padfield, A.]]
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[[Category: Parsons, R.]]
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[[Category: Radimerski, T.]]
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[[Category: Raynaud, F I.]]
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[[Category: Robertson, A.]]
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[[Category: Roughley, S D.]]
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[[Category: Rugaard-Jensen, M.]]
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[[Category: Schoepfer, J.]]
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[[Category: Simmonite, H.]]
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[[Category: Surgenor, A.]]
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[[Category: Valenti, M.]]
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[[Category: Walls, S.]]
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[[Category: Webb, P.]]
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[[Category: Wood, M.]]
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[[Category: Workman, P.]]
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[[Category: Wright, L M.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Atpase]]
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[[Category: Chaperone]]
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[[Category: Cytoplasm]]
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[[Category: Heat shock]]
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[[Category: Hsp90]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Pu3]]
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[[Category: Stress response]]

Revision as of 21:31, 26 December 2010

Image:2wi2.png

Template:STRUCTURE 2wi2

Contents

ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE

Template:ABSTRACT PUBMED 19610616

About this Structure

2wi2 is a 2 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2009 Jul 17. PMID:19610616 doi:10.1021/jm900357y

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