1nql
From Proteopedia
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[[Image:1nql.png|left|200px]] | [[Image:1nql.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_12620237}} | {{ABSTRACT_PUBMED_12620237}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypomagnesemia 4, renal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131530 131530]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nql]] is a 2 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQL OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:12620237</ref><references group="xtra"/> | <ref group="xtra">PMID:12620237</ref><references group="xtra"/> | ||
| + | [[Category: Epidermal Growth Factor Receptor]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Ferguson, K M.]] | [[Category: Ferguson, K M.]] | ||
[[Category: Lemmon, M A.]] | [[Category: Lemmon, M A.]] | ||
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[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Growth factor]] | [[Category: Growth factor]] | ||
| + | [[Category: Hormone/growth factor receptor complex]] | ||
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:35:32 2009'' | ||
Revision as of 22:01, 26 December 2010
Contents |
Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.
Template:ABSTRACT PUBMED 12620237
About this Structure
1nql is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell. 2003 Feb;11(2):507-17. PMID:12620237
