1t32

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[[Image:1t32.png|left|200px]]
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==About this Structure==
==About this Structure==
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1T32 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T32 OCA].
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[[1t32]] is a 1 chain structure of [[Cathepsin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T32 OCA].
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==See Also==
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*[[Cathepsin]]
==Reference==
==Reference==
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[[Category: Sukumar, N.]]
[[Category: Sukumar, N.]]
[[Category: Wells, G I.]]
[[Category: Wells, G I.]]
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[[Category: Hydrolase]]
[[Category: Inflammation inhibitor serine protease]]
[[Category: Inflammation inhibitor serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:27:53 2009''
 

Revision as of 22:17, 26 December 2010

Template:STRUCTURE 1t32

Contents

A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation

Template:ABSTRACT PUBMED 15741158

About this Structure

1t32 is a 1 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • de Garavilla L, Greco MN, Sukumar N, Chen ZW, Pineda AO, Mathews FS, Di Cera E, Giardino EC, Wells GI, Haertlein BJ, Kauffman JA, Corcoran TW, Derian CK, Eckardt AJ, Damiano BP, Andrade-Gordon P, Maryanoff BE. A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J Biol Chem. 2005 May 6;280(18):18001-7. Epub 2005 Feb 28. PMID:15741158 doi:10.1074/jbc.M501302200
  • Hof P, Mayr I, Huber R, Korzus E, Potempa J, Travis J, Powers JC, Bode W. The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities. EMBO J. 1996 Oct 15;15(20):5481-91. PMID:8896442

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