2opr
From Proteopedia
(Difference between revisions)
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[[Image:2opr.png|left|200px]] | [[Image:2opr.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2opr]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:17441703</ref><references group="xtra"/> | <ref group="xtra">PMID:17441703</ref><references group="xtra"/> | ||
| - | [[Category: | + | [[Category: Hiv-1 m:b_hxb2r]] |
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] | ||
[[Category: Chamberlain, P P.]] | [[Category: Chamberlain, P P.]] | ||
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[[Category: Hiv-1 reverse transcriptase]] | [[Category: Hiv-1 reverse transcriptase]] | ||
[[Category: Nnrti]] | [[Category: Nnrti]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 22:34, 26 December 2010
Contents |
Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.
Template:ABSTRACT PUBMED 17441703
About this Structure
2opr is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.
See Also
Reference
- Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. J Med Chem. 2007 May 17;50(10):2301-9. Epub 2007 Apr 19. PMID:17441703 doi:http://dx.doi.org/10.1021/jm061117m
