2fl6

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Revision as of 23:04, 26 December 2010

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Template:STRUCTURE 2fl6

Contents 1 crystal structure of KSP in complex with inhibitor 6 2 About this Structure 3 See Also 4 Reference

crystal structure of KSP in complex with inhibitor 6

Template:ABSTRACT PUBMED 16439123

About this Structure

2fl6 is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Kinesin

Reference

• Fraley ME, Garbaccio RM, Arrington KL, Hoffman WF, Tasber ES, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Fernandes C, Schaber MD, Lobell RB, Tao W, South VJ, Yan Y, Kuo LC, Prueksaritanont T, Shu C, Torrent M, Heimbrook DC, Kohl NE, Huber HE, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1775-9. Epub 2006 Jan 24. PMID:16439123 doi:10.1016/j.bmcl.2006.01.030