2q1l
From Proteopedia
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[[Image:2q1l.png|left|200px]] | [[Image:2q1l.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_17574412}} | {{ABSTRACT_PUBMED_17574412}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Statins, attenuated cholesterol lowering by OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142910 142910]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2q1l]] is a 4 chain structure of [[HMG-CoA Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1L OCA]. | |
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| + | ==See Also== | ||
| + | *[[HMG-CoA Reductase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Statin]] | [[Category: Statin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 22:19:41 2009'' | ||
Revision as of 23:06, 26 December 2010
Contents |
Design and Synthesis of Pyrrole-based, Hepatoselective HMG-CoA Reductase Inhibitors
Template:ABSTRACT PUBMED 17574412
About this Structure
2q1l is a 4 chain structure of HMG-CoA Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Pfefferkorn JA, Song Y, Sun KL, Miller SR, Trivedi BK, Choi C, Sorenson RJ, Bratton LD, Unangst PC, Larsen SD, Poel TJ, Cheng XM, Lee C, Erasga N, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu G, Robertson A, Olsen K, Mertz T, Sekerke C, Pavlovsky A, Harris MS, Bainbridge G, Caspers N, Chen H, Eberstadt M. Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4538-44. Epub 2007 Jun 6. PMID:17574412 doi:10.1016/j.bmcl.2007.05.096
