1gj4
From Proteopedia
(Difference between revisions)
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[[Image:1gj4.png|left|200px]] | [[Image:1gj4.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1gj4]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ4 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hirudin]] | ||
==Reference== | ==Reference== | ||
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[[Category: Sprengeler, P A.]] | [[Category: Sprengeler, P A.]] | ||
[[Category: Verner, E.]] | [[Category: Verner, E.]] | ||
| + | [[Category: Blood clotting]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Oxyanion hole water]] | [[Category: Oxyanion hole water]] | ||
[[Category: Shift of pka of his57]] | [[Category: Shift of pka of his57]] | ||
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[[Category: Very short hydrogen bond]] | [[Category: Very short hydrogen bond]] | ||
[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:16:48 2009'' | ||
Revision as of 00:22, 27 December 2010
Contents |
SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN
Template:ABSTRACT PUBMED 11731301
About this Structure
1gj4 is a 3 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301
Categories: Homo sapiens | Thrombin | Allen, D. | Breitenbucher, J G. | Hui, H. | Katz, B A. | Luong, C. | Mackman, R L. | Martelli, A. | McGee, D. | Spencer, J R. | Sprengeler, P A. | Verner, E. | Blood clotting | Hydrolase | Oxyanion hole water | Shift of pka of his57 | Specificity | Structure-based drug design | Three-centered | Trypsin | Urokinase | Very short hydrogen bond | Zn+2-mediated inhibition
