1r49

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{{Seed}}
 
[[Image:1r49.png|left|200px]]
[[Image:1r49.png|left|200px]]
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{{ABSTRACT_PUBMED_14594810}}
{{ABSTRACT_PUBMED_14594810}}
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==Disease==
 
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Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126420 126420]]
 
==About this Structure==
==About this Structure==
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1R49 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R49 OCA].
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[[1r49]] is a 3 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R49 OCA].
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==See Also==
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*[[Topoisomerase]]
==Reference==
==Reference==
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[[Category: Quigley, P M.]]
[[Category: Quigley, P M.]]
[[Category: Dna]]
[[Category: Dna]]
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[[Category: Isomerase/dna complex]]
[[Category: Protein]]
[[Category: Protein]]
[[Category: Topoisomerase i]]
[[Category: Topoisomerase i]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:41:38 2009''
 

Revision as of 00:24, 27 December 2010

Template:STRUCTURE 1r49

Contents

Human topoisomerase I (Topo70) double mutant K532R/Y723F

Template:ABSTRACT PUBMED 14594810

About this Structure

1r49 is a 3 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Interthal H, Quigley PM, Hol WG, Champoux JJ. The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J Biol Chem. 2004 Jan 23;279(4):2984-92. Epub 2003 Oct 31. PMID:14594810 doi:10.1074/jbc.M309959200

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