3kw9

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Revision as of 00:41, 27 December 2010

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Template:STRUCTURE 3kw9

Contents 1 X-ray structure of Cathepsin K covalently bound to a triazine ligand 2 About this Structure 3 See Also 4 Reference

X-ray structure of Cathepsin K covalently bound to a triazine ligand

Template:ABSTRACT PUBMED 20149657

About this Structure

3kw9 is a 1 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cathepsin

Reference

• Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Hamilton E, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Scullion P, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Bruin J, Hamilton W, Uitdehaag J, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1524-7. Epub 2010 Jan 25. PMID:20149657 doi:10.1016/j.bmcl.2010.01.100