2eb3
From Proteopedia
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[[Image:2eb3.png|left|200px]] | [[Image:2eb3.png|left|200px]] | ||
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===Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP=== | ===Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2eb3]] is a 1 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EB3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 15:47:58 2008'' | ||
Revision as of 00:49, 27 December 2010
Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP
About this Structure
2eb3 is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Kukimoto-Niino, M. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Senba, K. | Shirouzu, M. | Yamamoto, T. | Yokoyama, S. | Yoshikawa, S. | Atp-binding | Cell cycle | Disease mutation | Ec 2 7.10 1 | Kinase | National project on protein structural and functional analyse | Nppsfa | Phosphorylation | Receptor | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic | Transferase | Transmembrane | Tyrosine-protein kinase
