1jlb
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1jlb]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. The September 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Reverse Transcriptase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_9 10.2210/rcsb_pdb/mom_2002_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLB OCA]. | |
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| + | ==See Also== | ||
| + | *[[Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Non-nucleoside inhibitor]] | [[Category: Non-nucleoside inhibitor]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 01:58, 27 December 2010
Contents |
CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE
Template:ABSTRACT PUBMED 11575933
About this Structure
1jlb is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. The September 2002 RCSB PDB Molecule of the Month feature on Reverse Transcriptase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_9. Full crystallographic information is available from OCA.
See Also
Reference
- Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:11575933 doi:http://dx.doi.org/10.1006/jmbi.2001.4988
Categories: Hiv-1 m:b hxb2r | RCSB PDB Molecule of the Month | RNA-directed DNA polymerase | Reverse Transcriptase | Bird, L. | Chamberlain, P. | Nichols, C. | Ren, J. | Short, S. | Stammers, D K. | Stuart, D I. | Weaver, K. | Aid | Drug design | Drug resistance mutation | Hiv-1 reverse transcriptase | Nevirapine | Non-nucleoside inhibitor | Transferase
