2q38
From Proteopedia
(New page: 200px<br /> <applet load="2q38" size="450" color="white" frame="true" align="right" spinBox="true" caption="2q38, resolution 1.95Å" /> '''Carbonic Anhydrase ...) |
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| - | [[Image:2q38. | + | [[Image:2q38.jpg|left|200px]]<br /><applet load="2q38" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2q38" size=" | + | |
caption="2q38, resolution 1.95Å" /> | caption="2q38, resolution 1.95Å" /> | ||
'''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''<br /> | '''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''<br /> | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]] | ||
==About this Structure== | ==About this Structure== | ||
| - | 2Q38 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ZN, HG, LSA, BEZ and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http:// | + | 2Q38 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene>, <scene name='pdbligand=LSA:'>LSA</scene>, <scene name='pdbligand=BEZ:'>BEZ</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q38 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: ten stranded twisted beta sheet]] | [[Category: ten stranded twisted beta sheet]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:57:42 2008'' |
Revision as of 10:57, 23 January 2008
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Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom
About this Structure
2Q38 is a Single protein structure of sequence from Homo sapiens with , , , and as ligands. Active as Carbonate dehydratase, with EC number 4.2.1.1 Full crystallographic information is available from OCA.
Reference
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204
Page seeded by OCA on Wed Jan 23 12:57:42 2008
Categories: Carbonate dehydratase | Homo sapiens | Single protein | Heine, A. | Klebe, G. | Wischeler, J.Schulze. | BEZ | GOL | HG | LSA | ZN | Lyase | Ten stranded twisted beta sheet
